Ok, I've read the first few chapters, so I thought I'd post my thoughts currently.
Generally, I think it might be a little crunchy for my own tastes, but I suppose I'll see more if that plays out the further I get in. It kind of reminds me of the Traveller system for rolling, basically almost always 2 dice, beat a DC. At first glance I think the Level of Difficulty table seemed liked needless complexity. Your attributes give you bonus to your die rolls, but instead of it being a flat bonus, the DC for an Easy, Common, Taxing, Difficult, Backbreaking, Unmanageable task also gets higher the higher your bonus is. The math still works out that the better your bonus the easier it is to make, but it seemed needlessly complicated at first glance, and this would definitely be a table I'd want on my GM screen. On the attribute examples, I did like that you had examples laid out for what would be considered Common, Taxing, Difficult, Backbreaking, Unmanageable, and one not on the Level of Difficulty chart. I was cross-referencing as I was reading. I was unsure why it went higher than the chart, and didn't have one that lined up with Easy. Or maybe it lines up with the chart as if your attribute had a +3?
I thought it was an interesting system that your attributes have their own dice size too. Mortal attributes have you roll 2d6, gifted 2d8, and supernal 2d10. I haven't gotten into how you figure that out yet, but it seems like a nifty idea, and it was also something I was trying to keep in mind while looking at the LoD chart.
I also liked that you took the (Dis)Advantage system from 5e. Nice grab.
Some wording I thought was unnecessarily terse. At first read I wasn't sure how Sets and Helping worked, but after a careful reread I think I got it. I think I would just go into a little more depth on them.
I thought your examples that you wrote out were all nice! I also enjoyed the Summaries at the end of each chapter.
9 Attributes that I thought were pretty easy to understand: Agility, Charisma, Constitution, Influence, Intuition, Logic, Perception, Resolve, Strength. Corresponding charts for DCs using that ability were also nice. The only one I didn't quite get was Intuition, DC15: Conceal item while forcefully stripsearched. It didn't seem to line up with Intuition very well in my mind, but maybe I'll learn more as I read more. I also thought that maybe you could lose an attribute or 2. A couple seemed to be overlapping.
I thought the Health Level system was very interesting, and I'm looking forward to reading more about it. The table for At Deaths Door was also pretty cool. Talents and Ambitions seemed to call back to narrative based games like Dungeon World or even the Burning Wheel. I'm interested to see how those play in once I get more into it.
Basically, I'm just a few chapters in. Its a pretty easy read and well formatted. There were a few grammatical and spelling errors that an editor might help with (and sorry I forgot to jot them down). I'm worried some of it might be too crunchy for me personally, but it seems extremely unique and I'm looking forward to reading more. I would recommend others to look it over themselves too.
I'll write back more once I've read some more.